Figure 5

Hepatic metabolic parameters in Pemt^−/− and Tgh^−/−/Pemt^−/− mice fed HFD for 10 weeks.

(a) Livers from WT, Pemt^−/− and Tgh^−/−/Pemt^−/− mice. (b) Plasma ALT in WT, Pemt^−/− and Tgh^−/−/Pemt^−/− mice. (c) Liver/ body weight ratio in WT, Pemt^−/− and Tgh^−/−/Pemt^−/− mice. (d) Liver TG, CE, FC and TC mass in WT, Pemt^−/− and Tgh^−/−/Pemt^−/− mice. (e) Plasma ketone bodies concentrations in WT, Tgh^−/−, Pemt^−/− and Tgh^−/−/Pemt^−/− mice. n = 5, 6. Data are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 vs WT control.