Table 2 PCA3 stratified analysis.
Data sets | Sensitivity (95% CI) | Specificity (95% CI) | Diagnostic OR (95% CI) | I2, %* | AUC (95% CI) | |
|---|---|---|---|---|---|---|
Total | 43 | |||||
Design | ||||||
Case-control | 8 | 0.63 (0.61–0.66) | 0.88 (0.87–0.90) | 10.36 (5.51–21.25) | 36.9 | 0.82 (0.79–0.85) |
Prospective | 39 | 0.65 (0.63–0.66) | 0.73 (0.72–0.74) | 5.31 (4.19–6.73) | 70.5 | 0.75 (0.74–0.76) |
biopsy | ||||||
Initial* | 14 | 0.65 (0.63–0.67) | 0.82 (0.81–0.83) | 8.14 (4.78–13.86) | 51.8 | 0.80 (0.78–0.82) |
Repeated* | 11 | 0.58 (0.55–0.62) | 0.69 (0.67–0.71) | 3.19 (2.62–3.83) | 0 | 0.68 (0.67–0.70) |
Mixed | 22 | 0.66 (0.64–0.68) | 0.68 (0.67–0.69) | 5.13 (3.99–6.60) | 76.9 | 0.75 (0.74–0.76) |
cut-off value | ||||||
Equal 35 | 26 | 0.63 (0.62–0.65) | 0.74 (0.73–0.75) | 4.75 (3.42–6.60) | 64.1 | 0.74 (0.73–0.76) |
Not equal 35 | 21 | 0.70 (0.68–0.73) | 0.67 (0.65–0.69) | 6.22 (4.62–8.37) | 62.6 | 0.77 (0.76–0.79) |
