Table 3 Blood pressure change in hypertension after acupuncture treatment.

From: A Targeted Metabolomics MRM-MS Study on Identifying Potential Hypertension Biomarkers in Human Plasma and Evaluating Acupuncture Effects

Parameters

Baseline (n = 113)

Post-treatment (n = 108)

P value

24-hour SBP∇

145.1 ± 9.28

140.7 ± 9.59

 < 0.0001**

24-hour DBPΔ

88.35 ± 7.92

85.86 ± 7.95

0.0024**

Day SBP

147.8 ± 9.77

143.3 ± 10.28

 < 0.0001**

Day DBP

90.08 ± 8.25

87.67 ± 8.19

0.0033**

Night SBP

135.6 ± 13.23

132.4 ± 13.04

0.0130*

Night DBP

82.11 ± 8.91

79.93 ± 9.57

0.0474*

SBP Variability (%)

15.22 ± 4.938

16.55 ± 5.352

0.2755

DBP Variability (%)

19.67 ± 8.399

19.51 ± 6.336

0.9326

MAP▲

103.5 ± 12.77

102.2 ± 6.302

0.7383

Pulse (beats/min)

71.57 ± 7.068

76.36 ± 8.599

0.0151*

Nocturnal Dipping (SBP)

8.07 ± 8.53

7.52 ± 7.67

0.4267

Nocturnal Dipping (DBP)

8.68 ± 7.90

8.78 ± 7.30

0.9688

SBP mensor ± SE

145.61 ± 0.95

138.50 ± 1.03

 < 0.0001

SBP amplitude (95% CL)

13.01 (8.12, 17.91)

7.94 (2.61, 13.26)

/

SBP acrophase (95% CL)

−214.74 (−236.85, −192.63)

−232.89 (−275.08, −270.02)

/

DBP mensor ± SE

84.86 ± 0.65

82.10 ± 0.62

0.0051

DBP amplitude (95% CL)

7.20 (3.85, 10.56)

5.72 (2.51, 8.94)

/

DBP acrophase (95% CL)

−198.30 (−226.09, −180.09)

−243.09 (−277.28, −270.10)

/

Blood sugar (mmol/L)

5.04 ± 0.30

5.02 ± 0.27

0.944

Total Cholesterol (mmol/L)

4.82 ± 0.55

4.73 ± 0.47

0.409

RBC count (×1012/L)

4.34 ± 0.18

4.33 ± 0.30

0.952

WBC count (×109/L)

5.16 ± 0.98

4.49 ± 0.84

0.005**

ALT (unit/L)

32.44 ± 11.23

24.67 ± 6.00

0.046*

AST (unit/L)

27.22 ± 7.17

26.56 ± 7.33

0.764

BUN (mmol/L)

5.91 ± 1.43

5.24 ± 1.17

0.029*

sCr (μmol/L)

71.07 ± 10.63

68.59 ± 12.49

0.551

Serum uric acid (μmol/L)

251.9 ± 83.82

254.3 ± 61.56

0.823

HDL-C (mmol/L)

1.17 ± 0.22

1.02 ± 0.15

0.096

LDL-C (mmol/L)

2.87 ± 0.45

2.69 ± 0.40

0.173

  1. ∇: Systolic blood pressure; Δ: Diastolic blood pressure; ▲: Mean Arterial Pressure; *P < 0.05; **P < 0.01. Nocturnal Dipping = (daytime BP-nighttime BP)/daytime BP; Reverse-dipper: <0% nocturnal SBP fall; Nondippers: with ≥0% but <10%; Dippers: with ≥10% but <20%; extreme-dippers: with ≥20%.
  2. RBC: red blood cell; WBC: white blood cell; ALT: Alanine Aminotransferase; AST: Aspartate Aminotransferase; BUN: blood urea nitrogen; Scr: HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.
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