Figure 7: Efficacy of B2088-gatifloxacin combination in mammalian cell culture and mice model of bacterial keratitis. | Scientific Reports

Figure 7: Efficacy of B2088-gatifloxacin combination in mammalian cell culture and mice model of bacterial keratitis.

From: Branched Peptide, B2088, Disrupts the Supramolecular Organization of Lipopolysaccharides and Sensitizes the Gram-negative Bacteria

Figure 7

Decreased intracellular bacterial load by B2088 in combination with (a) gatifloxacin and (b) Tobramycin in infectedA549 cells. *Represents p < 0.05. Slit lamp biomicrocopy of mice treated with (c) PBS, (d) 0.3% gatifloxacin and (e) B2088 (0.05%) and 0.15% gatifloxacin after 3 days post treatment. (f) Bacterial burden in the untreated and treated cornea on days 1, 2 and 3 post infection. The pink bar indicates the average value.

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