Figure 5: Intraretinal axonal trajectories are disturbed in E13.5 Polμ−/− retinas.
From: Increased neuronal death and disturbed axonal growth in the Polμ-deficient mouse embryonic retina
Whole-mount retinas were stained with TUJ-1 to visualize RGC axonal trajectories. Histogram (a) shows the proportion and the absolute number of retinas with each phenotype. (b–f) Representative dorsal retina fields in WT (c,e) and Polμ−/− (b,d,f) mice. The asterisk marks the position of the optic nerve head. Axonal fasciculation was classified as severely defective (b), mildly defective (c,d), or normal (e,f), and plotted accordingly (a).
