Figure 6 | Scientific Reports

Figure 6

From: Catheter-based Intramyocardial Injection of FGF1 or NRG1-loaded MPs Improves Cardiac Function in a Preclinical Model of Ischemia-Reperfusion

Figure 6

Effect of FGF1 and NRG1-MP on cardiac fibrosis.

(A) Representative images showing the infarcted area three months after treatment stained with Sirius Red in sections of each group of animals. (B) Quantification of collagen deposition in the infarcted zones 3 months after growth factor loaded MP or control-MP injection. Data are means ± SEM. (Kolmogorov-Smirnov test showed no Gaussian distribution and the non-parametric Kruskal Wallis test was used; *p < 0.05). (C) Correlation between functional echocardiographic parameters and % fibrosis between MRG1-MP and Control-MP (Pearson Correlation analysis R = −0.6052; p = 0.0485).

Back to article page