Figure 4: 2-O-Bn-InsP5 inhibits EGF-induced calcium release in MDA-MB-231 and MDA-MB-435 cells. | Scientific Reports

Figure 4: 2-O-Bn-InsP5 inhibits EGF-induced calcium release in MDA-MB-231 and MDA-MB-435 cells.

From: A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

Figure 4

Calcium release assay performed in MDA-MB-231 (A–D) and MDA-MB-435 (E–H) treated with 2-O-Bn-InsP5 and InsP5 (50 μM). Arrows indicate the time point(s) of EGF and ATP stimulation. The chart is the mean ± SEM of 4 independent experiments; asterisks indicate P value; *<0.05; **≤0.01.

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