Figure 3
From: Loss of ubiquitin E2 Ube2w rescues hypersensitivity of Rnf4 mutant cells to DNA damage
Ube2w inactivation suppressed ΔRNF4 DNA damaged hypersensitivity.
Wild type cells and cells deficient for ΔRNF4, ΔUBE2W and ΔRNF4 ΔUBE2W were subjected to DNA damaged induced stress by mitomycin C, cisplatin, γ-irradiation, HU as indicated. X-axis indicated the increase range of concentration for each drug. Effect on each cell line is indicated of the percentage of colony formation on the Y-axis (logarithmic scale). DATA represented as indicated: Wild type (Blue losange), ΔRNF4 (red square), ΔUBE2W (brown circle), ΔRNF4 ΔUBE2W (green triangle). Error bars represent 2 SD.
