Table 5 Selected Gene Ontology (GO) terms significantly impacted by Haemonchus contortus infection in the resistant breed (CHB).
GO_id | Ontology | Description | Observed/Total | Z Score | P Value |
|---|---|---|---|---|---|
GO:0019369 | BP | arachidonic acid metabolic process | 10/36 | 4.95 | 1.13E-04 |
GO:0002673 | BP | regulation of acute inflammatory response | 15/38 | 7.93 | 1.16E-08 |
GO:0002675 | BP | positive regulation of acute inflammatory response | 8/13 | 7.78 | 4.69E-07 |
GO:0050727 | BP | regulation of inflammatory response | 24/135 | 5.01 | 1.53E-05 |
GO:0050900 | BP | leukocyte migration | 30/183 | 5.11 | 7.54E-06 |
GO:0043410 | BP | positive regulation of MAPK cascade | 30/197 | 4.65 | 3.28E-05 |
GO:0006956 | BP | complement activation | 14/33 | 8.06 | 1.18E-08 |
GO:0030449 | BP | regulation of complement activation | 11/23 | 7.75 | 9.91E-08 |
GO:0006957 | BP | complement activation, alternative pathway | 7/10 | 7.87 | 7.26E-07 |
GO:0006958 | BP | complement activation, classical pathway | 11/25 | 7.33 | 2.87E-07 |
GO:0031714 | MF | C5a anaphylatoxin chemotactic receptor binding | 5/5 | 8.21 | 1.55E-06 |
GO:0031715 | MF | C5L2 anaphylatoxin chemotactic receptor binding | 4/4 | 7.35 | 2.25E-05 |
GO:0007049 | BP | cell cycle | 119/1137 | 5.00 | 1.53E-06 |
GO:0022402 | BP | cell cycle process | 97/865 | 5.21 | 8.16E-07 |
GO:0008283 | BP | cell proliferation | 111/1013 | 5.34 | 3.84E-07 |
GO:0051301 | BP | cell division | 77/504 | 7.59 | 1.83E-11 |
GO:0051302 | BP | regulation of cell division | 23/140 | 4.47 | 8.26E-05 |
GO:0051321 | BP | meiotic cell cycle | 15/87 | 3.82 | 8.23E-04 |
GO:0031577 | BP | spindle checkpoint | 11/40 | 5.15 | 5.72E-05 |
GO:0007088 | BP | regulation of mitosis | 15/80 | 4.20 | 3.26E-04 |
GO:0042555 | CC | MCM complex | 5/11 | 5.05 | 5.03E-04 |
GO:0044818 | BP | mitotic G2/M transition checkpoint | 6/11 | 6.24 | 3.63E-05 |
GO:0007186 | BP | G-protein coupled receptor signaling pathway | 33/207 | 5.18 | 4.97E-06 |
GO:0043627 | BP | response to estrogen | 16/83 | 4.46 | 1.48E-04 |
GO:0001676 | BP | long-chain fatty acid metabolic process | 11/53 | 3.99 | 8.27E-04 |
GO:0033500 | BP | carbohydrate homeostasis | 15/81 | 4.14 | 3.75E-04 |
GO:0006865 | BP | amino acid transport | 14/71 | 4.27 | 2.97E-04 |
GO:0030141 | CC | secretory granule | 28/172 | 4.89 | 1.72E-05 |
GO:0051048 | BP | negative regulation of secretion | 12/57 | 4.22 | 4.23E-04 |
GO:0071229 | BP | cellular response to acid | 19/96 | 5.00 | 2.49E-05 |
GO:0001696 | BP | gastric acid secretion | 6/7 | 8.23 | 7.00E-07 |
