Figure 5 | Scientific Reports

Figure 5

From: Local anesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro

Figure 5

Bupivacaine treatment inhibited cell migration of both ovarian cancer (SKOV-3) and prostate cancer (PC-3) cells.

Scratched monolayer cells were treated with 1 mM bupivacaine for 24 h. Degree of wound healing was calculated as (initial wound area − remaining wound area)/initial wound area. (A) Bupivacaine suppressed wound closure in SKOV-3 cells. (B) Bupivacaine suppressed wound closure in PC-3 cells. All values are presented as mean ± SD (n = 4); ***P < 0.001.

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