Table 2 Area Under the ROC curves for advanced (stage 2 or 3) AKI, or Composite Outcome.

From: Urinary π-glutathione S-transferase Predicts Advanced Acute Kidney Injury Following Cardiovascular Surgery

 

T3

T6

T9

T12

T24

Advanced AKI

 α-GST

0.477 (0.267–0.686)

0.489 (0.301–0.678)

0.508 (0.349–0.668)

0.395 (0.205–0.584)

0.604 (0.416–0.791)

 adjusted α-GST$

0.395 (0.215–0.575)

0.435 (0.271–0.599)

0.448 (0.297–0.599)

0.366 (0.204–0.529)

0.515 (0.359–0.671)

 π-GST

0.784 (0.673–0.895)#

0.649 (0.456–0.843)

0.767 (0.610–0.924)#

0.552 (0.360–0.743)

0.597 (0.414–0.780)

 adjusted π-GST$

0.675 (0.546–0.804)*

0.529 (0.369–0.688)

0.587 (0.426–0.749)

0.384 (0.221–0.547)

0.413 (0.273–0.554)

Composite outcome

 α-GST

0.553 (0.366–0.739)

0.533 (0.372–0.693)

0.537 (0.398–0.676)

0.451 (0.286–0.616)

0.619 (0.462–0.775)

 adjusted α-GST$

0.455 (0.291–0.620)

0.448 (0.298–0.597)

0.454 (0.314–0.593)

0.397 (0.251–0.543)

0.513 (0.379–0.647)

 π-GST

0.783 (0.682–0.884)#

0.675 (0.512–0.837)*

0.763 (0.626–0.900)#

0.603 (0.432–0.774)

0.619 (0.461–0.777)

 adjusted π-GST$

0.670 (0.549–0.792)*

0.521 (0.375–0.667)

0.565 (0.415–0.714)

0.407 (0.255–0.558)

0.413 (0.280–0.545)

  1. Expressed as AUC (95% confidence interval); *p < 0.05, #p < 0.005 against AUC = 0.5 by C statistics.
  2. $concentration divided by urine creatinine level.
  3. GST, glutathione S-transferase.
  4. **labeled as 3 hours [T3], 6 hours [T6], 9 hours [T9], 12 hours later [T12], and 24 hours post-surgery [T24].
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