Figure 1 | Scientific Reports

Figure 1

From: Different prognostic value of circulating and disseminated tumor cells in primary breast cancer: Influence of bisphosphonate intake?

Figure 1

Prognostic significance of CTCs and DTCs with regard to PFS and OS.

Kaplan-Meier curves were drawn in order to compare PFS and OS with regard to CTCs in blood and DTCs in the BM. Whereas no significant associations could be shown for DTCs with regard to PFS [P = 0.7215; HR 0.916 (0.564–1.487)] and OS [P = 0.6953; HR 0.885 (0.481–1.630)], CTCs significantly correlated with PFS [P = 0.0227; HR 2.058 (1.106–3.828)] but not with OS [P = 0.267; HR1.588 (0.702–3.595)]. Univariable Cox Regression model-estimated survival curves. Dotted line = DTC negative patients [n = 314], longdashed line = DTC positive patients [n = 211], solid line = CTC negative patients [n = 292], mediumdashdotdot’ed line = CTC positive patients [n = 84].

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