Table 1 Description of datasets.

Dataset	n	Per district (n) ^c				Sex (%)		Age (in years) ^d
Dataset	n	*Larnaca/ Famagusta*	*Limassol*	*Nicosia*	*Paphos*	*Male*	*Female*	*Mean*	SD	*Median*
Patients	1184
β-thalassaemia	592	144	153	251	44	50.17	49.83	41.37	11.96	41
Hb H disease	595	209	98	256	13	49.16	50.84	36.87	19.71	34
Carriers	13824^a
α-thalassaemia	8412^b (out of 9287^a)	2065	1739	3401	534	44.83	55.17	36.74	12.31	35
β-thalassaemia	2335^b (out of 4700^a)	468	525	722	153	49.61	50.39	41.70	8.30	42
δ-thalassaemia	428^b (out of 504^a)	127	88	155	19	47.90	52.10	38.89	12.54	35

^aIncluding related individuals.
^bAfter filtering related individuals with the same genotype.
^cNumber of individuals per district, after filtering those in unidentified locations.
^dAge on 10 Dec 2015.

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