Table 2 Hemodynamic response to acute hypoxia in: HAPE susceptible (HAPE-S) and HAPE resistant (HAPE-R) subjects.

From: Raised HIF1α during normoxia in high altitude pulmonary edema susceptible non-mountaineers

 

Normoxia

Hypoxia

HAPE-S (n = 11)

HAPE-R (n = 11)

HAPE-S (n = 11)

HAPE-R (n = 11)

HR (beats/min)

68 ± 5.9

60.9 ± 6.1a

83.9 ± 10*

70.4 ± 9.6*a1

SBP (mm Hg)

123.1 ± 8.4

120.3 ± 11.9

128.4 ± 11

119.9 ± 8.9

DBP (mm Hg)

71 ± 5.8

67.2 ± 3.8

75.2 ± 6.5

66.4 ± 6.2a1

Spo2 (%)

98.4 ± 1.4

98.5 ± 0.8

66.9 ± 11.7*

78.7 ± 3.8*a1

sPpa (mm Hg)

28.2 ± 6.2

22.4 ± 4.6a

42.2 ± 9.5*

28.4 ± 6.1*a1

Ppa (mm Hg)

19.2 ± 3.7

15.7 ± 2.8a

27.9 ± 6*

19.3 ± 3.7*a1

  1. Values are presented as Mean ± SD. HR: heart rate; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; Spo2: Peripheral oxygen saturation; sPpa: pulmonary artery systolic pressure; Ppa: Pulmonary artery pressure.
  2. ap < 0.05 (HAPE-S versus HAPE-R under normoxia); a1p < 0.05 (HAPE-S versus HAPE-R under hypoxia). *normoxia vs hypoxia.
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