Figure 1: Analysis of CASC2 expression in both CRC tissues and cell lines.

(A) CASC2 was significantly down-regulated in 76% (52/68) of CRC tissues. The blue shading indicates the down-regulation of CASC2, and the data are presented as fold-change in tumor tissues relative to normal tissues. Pā<ā0.001, paired t-test. (B) Different CASC2 expression levels in CRC tissues and adjacent normal tissues from 68 patients as assessed by real-time PCR. *Pā<ā0.05, paired t-test. (C) Relative expression of CASC2 in five CRC cell lines (CACO2, SW480, SW620, HCT116 and HT-29) and non-tumorigenic human cell lines (CCC-HIE-2 and HER293). *Pā<ā0.05, Two-side Studentās t-test; nā=ā3.