Table 2 SNPs related with sensitivity to radio-chemotherapy in squamous cell carcinoma.
Type | Gene | SNP | Genotype | case | β | SError | Chi square | Pr (>|z|) | OR |
|---|---|---|---|---|---|---|---|---|---|
Chemotherapy | XPC | rs2228000 | TT/TC | 44 | 0 | 1 | |||
CC | 35 | 1.37218 | 0.533381 | 6.618267 | 0.010094 | 3.943933 | |||
XPC | rs2228001 | CA | 35 | 0 | 1 | ||||
CC | 10 | 1.81918 | 0.8732 | 4.340363 | 0.037219 | 6.166825 | |||
TP73 | rs2273953 | CC | 44 | 0 | 1 | ||||
TT | 5 | 2.872139 | 1.283755 | 5.005493 | 0.025267 | 17.67478 | |||
MDM2 | rs2279744 | GG/TG | 64 | 0 | 1 | ||||
TT | 15 | 1.512488 | 0.669008 | 5.111178 | 0.023772 | 4.538006 | |||
PTEN | rs2299939 | CC | 48 | 0 | 1 | ||||
AA/CA | 31 | 1.456732 | 0.567494 | 6.589272 | 0.01026 | 4.29191 | |||
DNA-Pkcs | rs1234811 | AA/AG | 64 | 0 | 1 | ||||
AG | 15 | 1.440435 | 0.624202 | 5.32521 | 0.021019 | 4.222532 | |||
Radiotherapy | DNA-PKcs | rs8178085 | A | 82 | 0 | 1 | |||
CA | 6 | 2.250114 | 1.047174 | 4.617121 | 0.031654 | 9.488816 | |||
DNA-PKcs | rs12334811 | AA/GG | 69 | 0 | 1 | ||||
AG | 19 | 1.603029 | 0.800815 | 4.006994 | 0.045312 | 4.96806 |
