Table 1 Main effect of diagnosis, diagnosis-by-distance interaction and diagnosis-by-age-distance interaction revealed by three-way ANCOVA analysis.

Brain areas	L/R	Cluster Size	Peak coordinate			DOF	Partial η ²	F -value	P -value
Brain areas	L/R	Cluster Size	x	y	z	DOF	Partial η ²	F -value	P -value
Main effect of diagnosis
Fusiform gyrus	R	88	21	−48	−12	1	0.095	12.65	0.001
Inferior occipital gyrus	L	62	−51	−75	−12	1	0.088	11.64	0.001
Inferior occipital gyrus	R	41	51	−75	−9	1	0.083	10.90	0.001
Posterior inferior temporal gyrus	R	98	54	−63	−18	1	0.081	10.65	0.001
Cerebellum crusl	L	69	−57	−57	−27	1	0.068	8.83	0.004
Cerebellum 6	R	42	33	−54	−21	1	0.071	9.19	0.003
Diagnosis-by-distance interaction
Posterior cingulate cortex	L/R	212	−3	−51	21	2	0.117	15.96	<0.001
Medial prefrontal cortex	L/R	62	−3	54	9	2	0.070	9.15	<0.001
Anterior inferior temporal gyrus	L	81	−39	12	−42	2	0.084	11.03	<0.001
Diagnosis-by-age-by-distance interaction
Orbitofrontal gyrus	L/R	188	15	54	−12	4	0.068	4.44	0.002

Statistical significance level is corrected for multiple comparisons using Gaussian random theory with q < 0.05 (voxel p < 0.01, Z > 2.3). The peak coordinate is defined in MNI space. ANCOVA, analysis of covariance; L, left; R, right; DOF, degree of freedom.

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