Table 2 Gene test results and frequency of 200 clinical samples of CYP2C19 alleles (type-specific concordance among RT-LAMP, conventional PCR and direct sequencing).
RT-LAMP | Conventional PCR (n = 100) | Total | Sequencing (n = 100) | Total | Agreement (%) | Frequency (%) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
*1/*1 | *2/*2 | *3/*3 | *1/*2 | *1/*3 | *2/*3 | *1/*1 | *2/*2 | *3/*3 | *1/*2 | *1/*3 | *2/*3 | |||||
*1/*1 | 51 | 0 | 0 | 0 | 0 | 0 | 51 | 51 | 0 | 0 | 0 | 0 | 0 | 51 | 100% | 51% (F1) |
*2/*2 | 0 | 6 | 0 | 0 | 0 | 0 | 6 | 0 | 6 | 0 | 0 | 0 | 0 | 6 | 100% | 6% (F2) |
*3/*3 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 100% | 2% (F3) |
*1/*2 | 0 | 0 | 0 | 35 | 0 | 0 | 35 | 0 | 0 | 0 | 35 | 0 | 0 | 35 | 100% | 35% (F4) |
*1/*3 | 0 | 0 | 0 | 0 | 4 | 0 | 4 | 0 | 0 | 0 | 0 | 4 | 0 | 4 | 100% | 4% (F5) |
*2/*3 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 100% | 2% (F6) |
Total | 51 | 6 | 2 | 35 | 4 | 2 | 100 | 51 | 6 | 2 | 35 | 4 | 2 | 100 | 100% | 100% |
