Figure 1

PZI combined with Se improved the general characteristics and glucose metabolism in the KKAy mice.
(A) Food intake. (B) Drinking water volume. (C) Body weight (BW). (D) Body weight loss. (E) Weekly variations in the fasting blood glucose (FBG) levels. (F) The decreasing fasting blood glucose levels. (G) Muscle glycogen levels. The data are expressed as the mean ± SEM (n = 6). *P < 0.05, **P < 0.01 vs. the control group, #P < 0.05, ##P < 0.01 vs. the model group, &P < 0.01 vs. the PZI or Se group. Model: diabetic group; PZI + Se (L): PZI (50 U/kg/d) + Se (100 μg/kg/d); PZI + Se (H): PZI (100 U/kg/d) + Se (200 μg/kg/d).