Figure 4 | Scientific Reports

Figure 4

From: Protamine zinc insulin combined with sodium selenite improves glycometabolism in the diabetic KKAy mice

Figure 4

PZI combined with Se improved the ultrastructure of the pancreatic beta cells.

(A) Representative pictures of pancreatic β cells sections from each group (15,000×). The transparent arrow heads show the secretory granules in the β cell. (B) The secretory granules were analyzed in 10 randomly chosen images per group. The data are expressed as the mean ± SEM. *P < 0.05, **P < 0.01 vs. the control group, #P < 0.05, ##P < 0.01 vs. the model group. Model: diabetic group; PZI + Se (L): PZI (50 U/kg/d) + Se (100 μg/kg/d); PZI + Se (H): PZI (100 U/kg/d) + Se (200 μg/kg/d).

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