Figure 5
From: STMN1 Promotes Progesterone Production Via StAR Up-regulation in Mouse Granulosa Cells
STMN1 activates Star and Cyp11a1 transcription.
(a) In mouse primary GCs, STMN1 enhanced the transcriptional activities of Star and Cyp11a1 promoters four- and seven-fold. (b) To diminish the endogenous STMN1 effect, HEK293T, KGN and SVOG cells were also used, which confirmed the analogous results in mouse primary GCs. *P < 0.05, **P < 0.01.
