Table 4 Diagnostic performance of serum NDKA for the detection of advanced neoplasia and advanced adenomas based on the screening cohort.
From: Evaluation of serum nucleoside diphosphate kinase A for the detection of colorectal cancer
Cut-off (pg/mL) | Specificity% (95% CI) | Advanced neoplasia | Advanced adenomas | ||||
|---|---|---|---|---|---|---|---|
Sensitivity % (95% CI) | PPV % (95% CI) | NPV % (95% CI) | Sensitivity % (95% CI) | PPV % (95% CI) | NPV % (95% CI) | ||
≥62.59 a | 65.20 (60.6–69.6) | 63.16 (49.3–75.6) | 18.63 (13.3–24.8) | 93.35 (90.1–95.9) | 62.26 (47.9–75.2) | 17.35 (12.2–23.4) | 93.64 (90.4–96.1) |
≥76.07 | 85.02 (81.4–88.2) | 29.82 (18.4–43.4) | 20.07 (12.1–30.1) | 90.57 (87.4–93.2) | 30.19 (18.3–44.3) | 19.12 (11.3–29.1) | 91.21 (88.1–93.8) |
≥82.21 | 90.09 (87.0–92.7) | 24.56 (14.1–37.8) | 23.81 (13.6–36.6) | 90.45 (87.4–93.0) | 24.53 (13.8–38.3) | 22.50 (12.5–35.3) | 91.05 (88.1–93.6) |
≥94.79 | 95.15 (92.8–96.9) | 17.54 (8.7–29.9) | 31.32 (16.1–50.0) | 90.15 (87.2–92.7) | 16.98 (8.1–29.8) | 29.12 (14.2–48.0) | 90.71 (87.8–93.2) |
