Table 1 NMR structural statistics of apo p63-DBD.
From: Solution structure and binding specificity of the p63 DNA binding domain
SA | <SA>r | |||
|---|---|---|---|---|
RMSD from distance restraints (Å) 2 | ||||
all (554) | 0.029 ± 0.003 | 0.027 | ||
intra-residue (10) | 0.023 ± 0.008 | 0.025 | ||
inter-residue sequential (42) | 0.021 ± 0.002 | 0.023 | ||
medium range (89) | 0.033 ± 0.001 | 0.033 | ||
long range (335) | 0.032 ± 0.001 | 0.029 | ||
hbond (78) | 0.012 ± 0.001 | 0.010 | ||
RMSD from dihedral restraints (652) | 0.12 ± 0.01 | 0.11 | ||
RMSD J-coupling restraints (Hz) (48) | 0.82 ± 0.02 | 0.78 | ||
H-bond restraints average (Å/deg) (78) | 2.12 ± 0.2/16.0 ± 7.2 | 2.13 ± 0.1/13.3 ± 6.6 | ||
H-bond restraints min-max (Å/deg) | 1.42–2.58/5.3–38.2 | 1.83–2.56/1.5–35.7 | ||
Deviations from ideal covalent geometry | ||||
Bonds (Å × 10−3 ) | 4.88 ± 0.18 | 7.34 | ||
Angles (deg) | 0.73 ± 0.03 | 0.73 | ||
Impropers (deg) | 3.58 ± 1.08 | 1.53 | ||
Ramachandran Map regions (%) 3 | 88.9/9.6/0.7/0.8 | 88.4/10.6/0.0/1.0 | ||
SA vs. <SA> | SA vs. <SA> r | |||
Backbone | All | Backbone | All | |
0.35 ± 0.06 | 0.79 ± 0.09 | 0.42 ± 0.09 | 0.90 ± 0.18 | |
