Table 1 GO terms enriched with candidate genes for high-altitude adaptation in Tibetan sheep.
From: Genome-wide analysis reveals adaptation to high altitudes in Tibetan sheep
ID | Term | P value | P Bonferroni value | Associated genes |
---|---|---|---|---|
GO:0048667 | cell morphogenesis involved in neuron differentiation | 6.60E-05 | 0.0017 | CHN1, CNP, EPHA8, FGFR2, NUMBL, OMG, SOD1, SPTBN4, TBR1 |
GO:0022829 | wide pore channel activity | 7.23E-05 | 0.0017 | GJA3, GJB2, VDAC2 |
GO:0007409 | axonogenesis | 1.26E-04 | 0.0029 | CHN1, CNP, EPHA8, FGFR2, NUMBL, OMG, SPTBN4, TBR1 |
GO:0016877 | ligase activity, forming carbon-sulfur bonds | 5.51E-04 | 0.0121 | ACLY, ACSL6, SLC27A2 |
GO:0005681 | spliceosomal complex | 6.95E-04 | 0.0146 | DHX38, HNRNPK, RALY, SMNDC1, TXNL4B, U2AF1 |
GO:0001666 | response to hypoxia | 2.71E-02 | 0.0271 | EPAS1,CRYAA, LONP1 |
GO:0001894 | tissue homeostasis | 2.71E-02 | 0.0271 | EPAS1, PTHLH, SOD1 |
GO:0048469 | cell maturation | 2.71E-02 | 0.0271 | EPAS1, EPHA8, PPARG |