Table 3 The top 50 statistically significant KEGG classifications.
No. | Pathway | Pathway definition | Number of sequences |
|---|---|---|---|
1 | path: ko01100 | Metabolic pathways | 3371 (13.33%) |
2 | path: ko05146 | Amoebiasis | 1148 (4.54%) |
3 | path: ko05110 | Vibrio cholerae infection | 1092 (4.32%) |
4 | path: ko05016 | Huntington’s disease | 973 (3.85%) |
5 | path: ko04810 | Regulation of actin cytoskeleton | 950 (3.76%) |
6 | path: ko04510 | Focal adhesion | 910 (3.6%) |
7 | path: ko03040 | Spliceosome | 894 (3.53%) |
8 | path: ko05200 | Pathways in cancer | 879 (3.48%) |
9 | path: ko05169 | Epstein-Barr virus infection | 860 (3.4%) |
10 | path: ko03013 | RNA transport | 847 (3.35%) |
11 | path: ko00230 | Purine metabolism | 781 (3.09%) |
12 | path: ko04145 | Phagosome | 643 (2.54%) |
13 | path: ko04144 | Endocytosis | 638 (2.52%) |
14 | path: ko04270 | Vascular smooth muscle contraction | 633 (2.5%) |
15 | path: ko03010 | Ribosome | 632 (2.5%) |
16 | path: ko04530 | Tight junction | 616 (2.44%) |
17 | path: ko00240 | Pyrimidine metabolism | 616 (2.44%) |
18 | path: ko04142 | Lysosome | 610 (2.41%) |
19 | path: ko04141 | Protein processing in endoplasmic reticulum | 607 (2.4%) |
20 | path: ko05166 | HTLV-I infection | 596 (2.36%) |
21 | path: ko05168 | Herpes simplex infection | 593 (2.34%) |
22 | path: ko05132 | Salmonella infection | 576 (2.28%) |
23 | path: ko03015 | mRNA surveillance pathway | 563 (2.23%) |
24 | path: ko04120 | Ubiquitin mediated proteolysis | 557 (2.2%) |
25 | path: ko04010 | MAPK signaling pathway | 542 (2.14%) |
26 | path: ko04020 | Calcium signaling pathway | 538 (2.13%) |
27 | path: ko05414 | Dilated cardiomyopathy | 524 (2.07%) |
28 | path: ko05164 | Influenza A | 517 (2.04%) |
29 | path: ko05410 | Hypertrophic cardiomyopathy (HCM) | 495 (1.96%) |
30 | path: ko04970 | Salivary secretion | 493 (1.95%) |
31 | path: ko04976 | Bile secretion | 491 (1.94%) |
32 | path: ko05202 | Transcriptional misregulation in cancer | 484 (1.91%) |
33 | path: ko05010 | Alzheimer’s disease | 482 (1.91%) |
34 | path: ko05130 | Pathogenic Escherichia coli infection | 467 (1.85%) |
35 | path: ko04520 | Adherens junction | 467 (1.85%) |
36 | path: ko05152 | Tuberculosis | 464 (1.83%) |
37 | path: ko04910 | Insulin signaling pathway | 464 (1.83%) |
38 | path: ko04310 | Wnt signaling pathway | 438 (1.73%) |
39 | path: ko04110 | Cell cycle | 431 (1.7%) |
40 | path: ko04114 | Oocyte meiosis | 428 (1.69%) |
41 | path: ko04062 | Chemokine signaling pathway | 428 (1.69%) |
42 | path: ko04512 | ECM-receptor interaction | 424 (1.68%) |
43 | path: ko03020 | RNA polymerase | 423 (1.67%) |
44 | path: ko05100 | Bacterial invasion of epithelial cells | 411 (1.63%) |
45 | path: ko04971 | Gastric acid secretion | 410 (1.62%) |
46 | path: ko02010 | ABC transporters | 407 (1.61%) |
47 | path: ko03008 | Ribosome biogenesis in eukaryotes | 391 (1.55%) |
48 | path: ko05131 | Shigellosis | 374 (1.48%) |
49 | path: ko04972 | Pancreatic secretion | 372 (1.47%) |
50 | path: ko04666 | Fc gamma R-mediated phagocytosis | 367 (1.45%) |