Figure 2
Volume change comparison between PD patients with (pRBD) and without (noRBD) probable RBD in sub-cortical and cortical areas.
Thresholded t maps (at P < 0.05 corrected for multiple comparisons) superimposed onto Montreal Neurological Institute 152 brain imaging template. The color-coded bar represents t values and the display is thresholded at P < 0.05. (A) Areas of significantly smaller volume in pRBD. Upper level: Left, sagittal plane showing smaller volumes in the thalamus (arrow) and the anterior cingulate (arrow head). Middle, coronal plane showing smaller volumes in the putamen (arrow) and the claustrum (arrow head). Right, axial plane showing smaller volume in the posterior limb of the internal capsule (arrow). Lower level: Left, sagittal plane showing smaller volumes in the lingual gyrus (arrow) and the cerebellum (arrow head). Middle, coronal plane showing smaller volumes in the amygdala (arrow) and the hypothalamus (arrow head). Right, axial plane showing smaller volumes in the middle and anterior part of the superior longitudinal fasciculus (arrow) and the supramarginal gyrus (arrow head). (B) Areas of significantly larger volume in pRBD. Left, sagittal plane showing larger volume in an area encompassing the rectal gyrus and the orbitofrontal gyrus (arrow), the olfactory trigone (arrow head) and the medial prefrontal cortex (dashed arrow). Middle, coronal plane showing larger volume in the superior frontal gyrus (arrow) and the inferior frontal gyrus (arrow head). Right, axial plane showing larger volume in the mid-cingulate gyrus (arrow).
