Figure 2 | Scientific Reports

Figure 2

From: Donor CD47 controls T cell alloresponses and is required for tolerance induction following hepatocyte allotransplantation

Figure 2

Stimulation of anti-donor T cell responses by CD47KO but not WT hepatocyte transplantation.

Spleen cells were prepared from WT B6 mice 7 days after transplantation of WT or CD47KO OVA-Tg B6 hepatocytes and analyzed for proliferative responses of T cells to OVA or 3rd-party alloantigen by CFSE dilution assay. Shown are percentages (mean ± SDs) of proliferating cells in gated CD4+ (A) and CD8+ (B) T cell populations. *p < 0.05, **p < 0.01.

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