Table 1 Percentage Of Primary Sequence Identity of Human, Mouse, and Rat Nat Proteins against (Human)NAT1 Isoform and Probe NAT Substrate Specificities.

From: Treatment of Rats with Apocynin Has Considerable Inhibitory Effects on Arylamine N-Acetyltransferase Activity in the Liver

(HUMAN)NAT1

       

(HUMAN)NAT2

81

      

(MOUSE)NAT1

75

72

     

(MOUSE)NAT2

82

75

82

    

(MOUSE)NAT3

68

66

68

73

   

(RAT)NAT1

76

75

92

83

69

  

(RAT)NAT2

81

74

81

95

73

83

 

(RAT)NAT3

69

67

75

73

88

71

72

 

(HUMAN) NAT1

(HUMAN) NAT2

(MOUSE) NAT1

(MOUSE) NAT2

(MOUSE) NAT3

(RAT) NAT1

(RAT) NAT2

(RAT) NAT3

isoenzyme-selective substrate a

pABglu b

isoniazid

isoniazid

pABglu b

isoniazid

pABglu b

  1. aProbe substrates for each NAT isoenzyme are specified where available22,27.
  2. bpABglu = para-aminobenzoyl glutamate.