Figure 2: 5-NOT, colominic acid and vinorelbine enhance expression of NF-200 in the vicinity of lesion site.
From: The polysialic acid mimetics 5-nonyloxytryptamine and vinorelbine facilitate nervous system repair
(a,b) Laser scanning images of NF-200+ neurites projecting into the lesion site (R: rostral side; C: caudal side) in sagittal spinal cord sections. (a) Low magnification images. Arrows depict the lesion site. (b) High magnification images of the boxed areas in (a) are shown. Arrowheads point to NF-200 immuno-positive fibers. (c) NF-200 immunofluorescence intensity (mean values ± SEM, n = 4 per group) in the vicinity and within the lesion site in 5-NOT, vinorelbine and colominic acid (CA) treated mice as compared to vehicle control. (*p < 0.05, one-way ANOVA with Holm-Sidak post-hoc test). Scale bars: 100 μm.
