Figure 1 | Scientific Reports

Figure 1

From: Hyperlipidemia-associated gene variations and expression patterns revealed by whole-genome and transcriptome sequencing of rabbit models

Figure 1

Whole-genome sequencing of laboratory rabbits.

(a) Lipid profiles of standard chow-fed NZW, Chol-fed NZW and WHHL rabbits analyzed by high performance liquid chromatography. The Chol-fed NZW showed elevated β-VLDLs and the WHHL rabbits showed increased LDLs and reduced HDLs. (b) Cumulative distribution of depth of coverage for whole-genome sequencing. The average depth of coverage was 13×  for each individual rabbit. (c) Phylogenic tree of the rabbits. The tree was constructed on the basis of representative SNPs with the maximum likelihood method. Bootstrap values are marked on the branch. (d) Distribution of nucleotide diversity π. The statistics were calculated for every 100 kb sliding-window across the genome.

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