Figure 3

Serum analytes varying significantly with female hormonal status.

Robust regression was used where *follows the analyte name. The log₂ ratios of serum molecular concentrations of males, postmenopausal females and females taking the oral contraceptive pill (OC) compared to females with a menstrual cycle, shown in the plot with their 95% confidence intervals, were coefficients from the linear regression. Agreement with the validation cohort is shown by a ✓ in the last column. To the right of the plot, biomarkers of schizophrenia (SCZ), major depressive disorder (MDD) and cancer are indicated by ↑ (elevated in patients); ↓ (reduced in patients); or × (conflicting evidence for elevated and reduced levels in patients). Analyte abbreviations can be found in Supplementary Table 1.