Figure 4
From: Variation in serum biomarkers with sex and female hormonal status: implications for clinical tests
Average percentage of analytes falsely discovered between simulated patient and control groups with varying proportions of (A) males compared to females and (B) oral contraceptive pill (OC) users compared to females with menstrual cycles. Simulations represented biomarker studies for which there were no serum molecular differences between patient and control groups. For (A,B), the composition of the control group is shown on the x-axis, while the composition of the patient group is shown by lines of varying colours. Blue lines represent simulations with more (A) males or (B) OC users in the patient group, while red lines represent simulations with more (A) females or (B) females with menstrual cycles in the patient group. The y-axis shows the average percentage of analytes falsely discovered (p < 0.05) in each simulation.
