Figure 2 | Scientific Reports

Figure 2

From: Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization

Figure 2

Mice developed mechanical hypersensitivity after MPNL.

(A) The mechanical withdrawal threshold was evaluated using von Frey filaments before and from the 1st to 25th day after surgery. (B) The mechanical withdrawal threshold was evaluated before and at indicated time points after MPNL or CCI surgery. Sham-operated mice were used as the control. The data are presented as the mean ± S.E.M (n = 5 per group). Time 0 represents the baseline value before surgery. ***P < 0.001 and *P < 0.05 indicates a statistically significant difference when compared with the sham group. #P < 0.01 indicates a statistically significant difference when compared with the CCI group.

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