Figure 4 | Scientific Reports

Figure 4

From: Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization

Figure 4

ATF-3 immunoreactivity in the L4 DRG after MPNL or CCI.

At 3 or 7 days after MPNL or CCI surgery, L4 DRGs were harvested and the expression of ATF-3 was evaluated by immunofluorescence. ATF-3 was detected exclusively in the nuclei of neurons in the DRG. Representative images are shown in (A–F). (G) As a control, the primary antibody was omitted from the reaction. Scale bar 50 μm. (H) The percentages of ATF-3 + neurons are also shown. The data are presented as the mean ± S.E.M (n = 4 per group). ***P < 0.001 compared with naive mice. #P < 0.001 compared with MPNL mice.

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