Figure 5
From: The NKD1/Rac1 feedback loop regulates the invasion and migration ability of hepatocarcinoma cells
Ectopic expression of NKD1 inhibited HCC metastasis in vivo.
(A) A picture was drawn by us which describe the procedure of generating the nude mouse xenograft model. (B) The mice injected with SMMC-7721+Ctrl cells displayed more pulmonary and intra-hepatic micro-metastatic nodules and a higher metastasis rate than mice injected with SMMC-7721+NKD1. (C) Western blots analysis of the expression of NKD1 and Rac1 protein in SMMC-7721+Ctrl (the left four lanes) and SMMC-7721+NKD1 tumors (the right four lanes). (*P < 0.05).
