Figure 1

Concentration-effect relationship of compounds from BE-IS on LPS-induced the production of PGE2.
(A) Cytotoxic effects of compounds from BE-IS. Raw264.7 cells were treated with Sco, Umb, Esc, Hes and Cur individully or followed by 1 μg·mL−1 LPS for 24 h. Cells were then subjected to MTT assay as described in the Methods. (B–F) Concentration-effect relationship of Sco (B), Umb (C), Esc (D), Hes (E) and Cur (F) on LPS-induced the production of PGE2. Drugs were dissolved in DMSO and diluted in DMEM to a final value of DMSO <0.1%. All values are presented as the mean ± S.E. and are the result of three independent experiments.