Table 5 Coefficient correlation r, parameter m, median effective dosage D50 and Combination Index (CI).

From: Synergistic Effect of Compounds from a Chinese Herb: Compatibility and Dose Optimization of Compounds from N-Butanol Extract of Ipomoea stolonifera

 

Esc

Cur

Hes

E + C*

E + H*

C + H*

r

0.9917

0.9950

0.9949

0.9967

0.9952

0.9989

m

1.0840

1.0983

1.0451

1.0848

1.1095

1.0955

mlogD50

1.1178

0.5929

1.1709

0.7013

1.1774

0.8361

D50

10.7444

3.4660

13.1938

4.4308

11.5133

5.7971

Combination Index (CI)

Fa(%)

10

30

50

70

80

85

90

95

E+C*

0.7656

0.7736

0.7786

0.7837

0.7869

0.7890

0.7919

0.7964

E+H*

1.0517

0.9995

0.9684

0.9384

0.9199

0.9082

0.8929

0.8689

C+H*

0.9616

0.9471

0.9385

0.9303

0.9252

0.9220

0.9179

0.9114

  1. *E+C represent combination of Esc and Cur; E+H represent combination of Esc and Hes; C+H represent combination of Cur and Hes.
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