Table 1 Patient characteristics and descriptive statistics.

From: LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia

Variables

Patient Inflammation

P Value

With

Without

Patients

47

15

 

Age (y)

65.9 ± 8.12

60.3 ± 7.04

0.020

BMI (kg/m2)

28.4 ± 5.03

25.1 ± 4.27

0.026

Total PSA (ng/ml)

5.25 ± 3.22

4.71 ± 1.92

0.542

Prostate volume (ml)

58.3 ± 27.9

40.7 ± 16.2

0.024

IPSS-Total

17.2 ± 6.12

12.5 ± 5.16

0.009

 Incomplete emptying

1.85 ± 1.63

1.27 ± 1.05

0.202

 Frequency

3.46 ± 2.35

1.71 ± 1.26

0.008

 Intermittency

2.37 ± 2.65

3.05 ± 2.69

0.392

 Urgency

2.47 ± 2.01

1.03 ± 1.16

0.011

 Weak stream

2.78 ± 2.61

3.15 ± 3.03

0.647

 Straining

1.26 ± 1.83

0.97 ± 1.14

0.464

 Nocturia

2.97 ± 2.84

1.32 ± 1.56

0.036

IPSS-V

8.26 ± 4.45

8.44 ± 4.47

0.892

IPSS-S

8.90 ± 4.20

4.06 ± 2.57

 < 0.001

QOL score

4.18 ± 1.95

3.52 ± 1.87

0.254

Qmax (ml/s)

6.37 ± 4.74

7.48 ± 2.13

0.385

PVR (ml)

19.4 ± 8.72

22.3 ± 7.15

0.237

TLR4 mRNA expression level

4.92 ± 1.15

1.03 ± 0.27

 < 0.001

BAMBI mRNA expression level

0.46 ± 0.17

1.05 ± 0.22

 < 0.001

TLR4 staining score

5.13 ± 1.21

2.96 ± 0.73

 < 0.001

BAMBI staining score

3.63 ± 1.27

4.25 ± 1.10

0.095

p-Smad2/3 staining score

5.11 ± 1.48

3.37 ± 1.29

 < 0.001

  1. BMI, body mass index; PSA, prostate specific antigen; IPSS, International Prostate Symptom Score; V, voiding subscore; S, storage subscore; QOL, quality of life; Qmax, maximum flow rate; PVR, postvoid residual.
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