Figure 3 | Scientific Reports

Figure 3

From: The N-terminal zinc finger domain of Tgf2 transposase contributes to DNA binding and to transposition activity

Figure 3

Proposed model for Tgf2 transposition.

The cut-and-paste process contains four main stages: (1) pairing of transposases by dimerization or oligomerization, (2) DNA-specific binding of the transposases to the TE ends flanking the transposon, (3) cleavage of DNA strands at the ITR ends of the transposon and (4) capture of a new locus and integration of target DNA, purple block arrows indicated target site duplications (TSDs) in the host cell.

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