Figure 4
From: An isoform of Nedd4-2 is critically involved in the renal adaptation to high salt intake in mice
Plasma renin (a) and aldosterone (b) concentrations. Data are from normal salt wild-type mice (WT NS, n = 4), normal salt Nedd4-2 C2-knockout mice (KO NS, n = 5), high salt wild-type mice (WT HS, n = 3), high salt Nedd4-2 C2-knockout mice (KO HS, n = 6) and high salt Nedd4-2 C2-knockout mice treated with amiloride (KO HS+Amiloride, n = 5). (A) *p < 0.001 compared with KOxHS, KOxHS+Amiloride. (B) *p < 0.001 compared with WTxHS, KOxHS.
