Figure 6
From: An isoform of Nedd4-2 is critically involved in the renal adaptation to high salt intake in mice
(a) αENaC, (b) ENaC, (c) γENaC expression by immunohistochemistry. Data are from normal salt wild-type mice (WT NS, n = 8), high salt wild-type mice (WT HS, n = 6), normal salt Nedd4-2 C2-knockout mice (KO NS, n = 5) and high salt Nedd4-2 C2-knockout mice (KO HS, n = 6). (a) p = 0.001 WTxNS vs KOxHS, p = 0.002 WTxHS vs KOxHS. (b) p = 0.006 WTxNS vs KOxHS, p = 0.001 WTxHS vs KOxHS, p = 0.004 KOxNS vs KOxHS. (c) p < 0.001 WTxNS vs KOxHS, p = 0.005 WTxNS vs KOxNS.
