Figure 1 | Scientific Reports

Figure 1

From: miR-139-5p Inhibits the Epithelial-Mesenchymal Transition and Enhances the Chemotherapeutic Sensitivity of Colorectal Cancer Cells by Downregulating BCL2

Figure 1

miR-139-5p was downregulated in colorectal cancer.

(A) Heat map. miRNA microarray analyses were performed in six paired tumour and normal tissues. The green in the legend represents downregulation and the red represents upregulation. (B) Determination of miR-139-5p expression levels in eight colon cell lines and NCM460 cells (mean ± SEM). (C,D) Downregulation of miR-139-5p expression in primary colorectal cancer tissue compared their normal tissue (paired Student’s t-test). (E) miR-139-5p expression levels decreased significantly with the advance of the tumour stage.

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