Table 1 Characteristics of the study population.

From: CHRNA7 Polymorphisms and Dementia Risk: Interactions with Apolipoprotein ε4 and Cigarette Smoking

  

LOAD (N = 254)

VaD (N = 115 )

Control (N = 435)

  

mean ± SD

Age

 

79.8 ± 6.3

79.8 ± 6.1

73.2 ± 5.8

MMSE score

 

18.7 ± 5.1

15.2 ± 6.3

NA

SPMSQ (number of errors)

 

NA

NA

0.1 ± 0.4

  

N (%)

Female

 

162 (64)

66 (57)

232 (53)

Education

6 years

128 (51)

69 (60)

50 (12)

 

6–12 years

86 (34)

34 (30)

171 (39)

 

>12 years

37 (15)

12 (10)

212 (49)

Ever smoking

 

60 (24)

32 (28)

75 (17)

Alcohol consumption

 

28 (11)

19 (17)

48 (11)

Hypertension

 

96 (38)

75 (65)

232 (53)

Diabetes mellitus

 

48 (19)

40 (35)

62 (14)

Hypercholesterolemia

 

46 (18)

25 (22)

133 (31)

APOE ε4 status

 

99 (39)

26 (23)

65 (15)

  1. Cases (LOAD or VaD) were compared to controls. Numbers in bold indicate significant findings (P < 0.05). Abbreviations: LOAD, late-onset Alzheimer’s disease; VaD, vascular dementia; SD, standard deviation; MMSE, Mini-Mental State Exmination; SPMSQ, Short Portable Mental Status Questionnaire; NA, not applicable; APOE, apolipoprotein E.