Figure 4: Schematic representation of the main regulations observed at low and high pressure.
From: High hydrostatic pressure adaptive strategies in an obligate piezophile Pyrococcus yayanosii

Here are represented the formate metabolism (green), Mbh Hydrogenase (light orange), Mbx sulfhydrogenase (blue), SHI and SHII sulfhydrogenase (dark orange), the chemotaxis system along the archaellum, CRISPR/cas system, membrane-bound ATPase and the translation and replication complexes. The transcriptomic regulation is presented on the left whereas the proteomic one is on the right side. Blue and red arrows represent the sub- and over-expression in stress conditions (20 or 80 MPa) compared to the optimum condition (52 MPa). The circle and arrow lines correspond to the regulation at respectively 20 and 80 MPa. The differences observed for the CRISPR/cas system is due to the opposite regulations of the different clusters.