Table 5 Multivariable linear regression analyses demonstrating relationships of cholesterol efflux with high density lipoprotein (HDL) cholesterol, apolipoprotein A-I (apoA-I) and low-grade inflammation score in 293 subjects with metabolic syndrome (MetS) (A) and in 254 subjects without MetS (B).

	Model 1		Model 2		Model 3		Model 4
	β	P-value	β	P-value	β	P-value	β	P-value
(A) MetS (n = 293)
Age	0.053	0.35	0.049	0.40	0.076	0.17	0.067	0.24
Sex (men vs. women)	−0.029	0.63	−0.084	0.20	−0.003	0.96	−0.048	0.46
HDL cholesterol	0.305	<0.001	0.295	<0.001
ApoA-I					0.363	<0.001	0.356	<0.001
Low-grade inflammation score	−0.144	0.013	−0.156	0.007	−0.144	0.010	−0.151	0.009
(B) no MetS (n = 254)
Age	−0.006	0.92	0.002	0.97	−0.009	0.88	−0.006	0.92
Sex (men vs. women)	0.040	0.55	0.042	0.56	0.023	0.73	0.033	0.66
HDL cholesterol	0.414	<0.001	0.411	<0.001
ApoA-I					0.375	<0.001	0.376	<0.001
Low-grade inflammation score	0.079	0.197	0.105	0.096	0.045	0.46	0.069	0.28

β: standardized regression coefficient.
Models 1 include: age and sex, HDL cholesterol and low-grade inflammation score.
Models 2: additionally adjusted for current smoking, alcohol consumption, cardiovascular disease, glucose lowering drugs, lipid modifying drugs and antihypertensive medication.
Models 3 include: age and sex, apoA-I and low-grade inflammation score.
Models 4: additionally adjusted for current smoking, alcohol consumption, cardiovascular disease, glucose lowering drugs, lipid modifying drugs and antihypertensive medication.

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