Table 3 Cytotoxicity of compounds 2–4 against human tumour cell lines.

From: Penicimenolides A-F, Resorcylic Acid Lactones from Penicillium sp., isolated from the Rhizosphere Soil of Panax notoginseng

Compound

IC50 (μM)

MCF-7

U937

SH-SY5Y

HepG2

SW480

A549

2

9.89 ± 0.41

1.38 ± 0.18

44.41 ± 1.42

>100

22.66 ± 1.22

>100

3

11.59 ± 0.23

6.49 ± 0.41

47.62 ± 0.81

>100

24.82 ± 1.85

>100

4

10.47 ± 0.44

2.19 ± 0.074

73.47 ± 1.62

>100

41.18 ± 2.3

>100

Taxol

0.0152

0.0553

0.454

1.562

1.845

1.512

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