Figure 4: Clinical image atlas of VR-SIM versus histopathology images of benign and malignant prostate structures. | Scientific Reports

Figure 4: Clinical image atlas of VR-SIM versus histopathology images of benign and malignant prostate structures.

From: Gigapixel surface imaging of radical prostatectomy specimens for comprehensive detection of cancer-positive surgical margins using structured illumination microscopy

Figure 4

Arrows indicate corresponding features between VR-SIM and H&E-stained histology slides. (a,b) normal skeletal muscle, (c,d) nerves with ganglia, (e,f) neurovascular bundle, (g,h) smooth muscle bundle, (i,j) adipose tissue, (k,l) normal prostate glands with ‘cauliflower’ appearance, (m,n) benign prostate glands with elongated and rounded appearances, (o–r) examples of prostate adenocarcinoma, acinar type, Gleason grade 3 + 4 = 7.

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