Figure 6: Small molecule M1 mediated prevention of loss of GSIS in cholesterol enriched pancreatic beta cells.

(A) Pre-treatment with small molecule M1 prevents loss of GSIS in cholesterol enriched pancreatic beta cells. Chol: Cholesterol. (B) Proposed model of M1 mediated preservation of cellular respiration which prevents the loss of GSIS in cholesterol exposed pancreatic beta cells.