Figure 3: In vivo PET imaging of MI/reperfusion model with 18F-FDG. | Scientific Reports

Figure 3: In vivo PET imaging of MI/reperfusion model with 18F-FDG.

From: Identification of Angiogenesis Rich-Viable Myocardium using RGD Dimer based SPECT after Myocardial Infarction

Figure 3

(A–C) Serial PET scans were acquired at 7 (A), 14 (B) and 28 (C) days after MI/reperfusion. Shown are representative vertical long axis PET (left column), CT (middle column) and PET/CT fusion (right column) images from four independent experiments (n = 4 rats). 18F-FDG PET/CT was conducted with the identical animal at the same day of 99mTc-IDA-D-[c(RGDfK)]2 SPECT/CT imaging. The focal uptake of 18F-FDG (arrows) was seen in the identical region delineated by marked signal of 99mTc-IDA-D-[c(RGDfK)]2 in SPECT imaging. (D) 18F-FDG uptake ratio of hibernating to remote myocardium was peak at day 7 (1.64 ± 0.26) and gradually decreased similarly with 99mTc-IDA-D-[c(RGDfK)]2 SPECT imaging. Data are means ± SD (n = 4).

Back to article page