Figure 5: Immunohistochemical characterization of myocardium in MI/reperfusion model. | Scientific Reports

Figure 5: Immunohistochemical characterization of myocardium in MI/reperfusion model.

From: Identification of Angiogenesis Rich-Viable Myocardium using RGD Dimer based SPECT after Myocardial Infarction

Figure 5

Shown are representative photomicrographs of histologically stained cross sections of cardiac tissue isolated from MI/reperfusion model after in vivo SPECT and PET imaging. (A,B) Hematoxylin and eosin stained images display dense and aligned muscle structure in the remote myocardium (A) whereas loose and fibrous characteristics (asterisks) with abundance of micro-vessels (arrows) in the hibernating myocardium (B). (C,D) Immunohistochemical staining shows preferential expression of activated endothelial cell marker Integrin αvβ3 (brown color) in the hibernating myocardium, indicative of angiogenesis-rich characteristics.

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